Farnesyl transferase inhibitor, LB42708, Purity ≥98%

Synonym: 226929-39-1; LB-42708; LB 42708; [1-[[3-[(4-Bromophenyl)methyl]imidazol-4-yl]methyl]-4-naphthalen-1-ylpyrrol-3-yl]-morpholin-4-ylmethanone; Farnesyl transferase inhibitor

CAS Number: 226929-39-1
Compound CID: 10099206

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LB42708, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting farnesyl transferase. The molecular weight of the compound is 555.46, and its molecular formula is C₃₀H₂₇BrN₄O₂. It targets the FTase (H-ras), FTase (K-Ras) and FTase (N-ras).

Molecular Weight

555.46

Molecular Formula

C₃₀H₂₇BrN₄O₂

Targets

FTase (H-ras)

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 95 mg/mL (171.03 mM); Water: insoluble; Ethanol (warmed): 82 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

LB42708 can be used for its ability to enhance the efficacy of existing therapies.