Ferroptosis inhibitor, Erastin, Purity ≥98%

Synonym: 571203-78-6; CCG-269987; CS-1675; 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone; 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one; Ferroptosis inhibitor

MDL: MFCD09837984
CAS Number: 571203-78-6
Compound CID: 11214940

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Erastin, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting ferroptosis. The molecular weight of the compound is 547.04, and its molecular formula is C₃₀H₃₁ClN₄O₄.

Molecular Weight

547.04

Molecular Formula

C₃₀H₃₁ClN₄O₄

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 17 mg/mL (31.07 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 40% PEG 300 + 5% Tween80 + ddH₂O, 1.66 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Erastin displays the significant potential to act as an effective research tool to study ferroptosis and its mechanisms in various biological contexts.