FGFR inhibitor ASP5878, Purity ≥98%

Synonym: 1453208-66-6; FGFR inhibitor; ASP 5878; ASP-5878

CAS Number: 1453208-66-6
Compound CID: 71736582

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ASP5878, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, FGFR3, and FGFR4.

Molecular Weight

407.37

Molecular Formula

C₁₈H₁₉F₂N₅O₄

Targets

FGFR1: 0.47 nM; FGFR2: 0.6 nM; FGFR3: 0.74 nM; FGFR4: 3.5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 75 mg/mL (184.1 mM); Water: Insoluble; Ethanol: 4 mg/mL (9.81 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

ASP5878 serves as an FGFR inhibitor to explore therapeutic targets in FGFR-driven cancers.