FGFR inhibitor Brivanib alaninate, Purity ≥98%

Synonym: 649735-63-7; FGFR inhibitor; BMS582664

CAS Number: 649735-63-7
Compound CID: 11154925

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Brivanib alaninate, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, Flk1, VEGFR1, and VEGFR2.

Molecular Weight

441.5

Molecular Formula

C₂₂H₂₄FN₅O₄

Targets

FGFR1: 148 nM; Flk1: 89 nM; VEGFR1: 380 nM; VEGFR2: 25 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 83 mg/mL (188 mM); Water: Insoluble; Ethanol: 83 mg/mL (188 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Brivanib alaninate inhibits FGFR in research, providing insights into anti-cancer strategies targeting fibroblast growth factors.