FGFR inhibitor Debio-1347, Purity ≥98%

Synonym: 1265229-25-1; FGFR inhibitor; Debio 1347; Debio1347; CH5183284; CH 5183284; CH-5183284; FF-284; FF284; FF 284

MDL: MFCD28502053
CAS Number: 1265229-25-1
Compound CID: 66555680

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Debio-1347, soluble in DMSO and warmed ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, FGFR3, and FGFR4.

Molecular Weight

356.38

Molecular Formula

C₂₀H₁₆N₆O

Targets

FGFR1: 9.3 nM; FGFR2: 7.6 nM; FGFR3: 22 nM; FGFR4: 290 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 70 mg/mL (196.41 mM); Water: Insoluble; Warmed ethanol: 1 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Debio-1347 is used to investigate and inhibit FGFR, contributing to cancer research, specifically targeting tumors with FGFR genetic alterations.