FGFR inhibitor Derazantinib, Purity ≥98%

Synonym: 1234356-69-4; FGFR inhibitor; ARQ087; ARQ 087

CAS Number: 1234356-69-4
Compound CID: 46834118

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Derazantinib, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, and FGFR3.

Molecular Weight

468.57

Molecular Formula

C₂₉H₂₉FN₄O

Targets

FGFR1: 4.5 nM; FGFR2: 1.8 nM; FGFR3: 4.5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 80 mg/mL (170.73 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Derazantinib is applied in the study of FGFR as a selective inhibitor, offering potential therapeutic insights in oncology research, focusing on FGFR-driven cancers.