Properties
Description
FIIN-2, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, FGFR3, and FGFR4.
Molecular Formula
C35H38N8O4
Targets
FGFR1: 3.09 nM; FGFR2: 4.3 nM; FGFR3: 27 nM; FGFR4: 45.3 nM
Solubility
DMSO: 62 mg/mL (97.67 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
FIIN-2 is utilized in FGFR research to explore its inhibitory effects, particularly enhancing the understanding of FGFR’s role in oncogenesis.
