Properties
Description
NVP-BGJ398 phosphate is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, FGFR3, and FGFR4.
Molecular Formula
C26H34Cl2N7O7P
Targets
FGFR1: 0.9 nM; FGFR2: 1.4 nM; FGFR3: 1 nM; FGFR4: 60 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
NVP-BGJ398 phosphate is a selective FGFR inhibitor widely used in oncology research, particularly for studying its therapeutic potential in tumors with FGFR mutations.