FGFR inhibitor ODM-203, Purity ≥98%

Synonym: 1430723-35-5; FGFR inhibitor; ODM203; ODM 203

CAS Number: 1430723-35-5
Compound CID: 71554322

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ODM-203, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets DDR1, FGFR1, FGFR2, FGFR3, FGFR4, MAP4K4, MINK1, PDGFRα, RET, SIK3, and VEGFR1.

Molecular Weight

505.54

Molecular Formula

C₂₆H₂₁F₂N₅O₂S

Targets

DDR1: 6 nM; FGFR1: 11 nM; FGFR2: 16 nM ; FGFR3: 6 nM; FGFR4: 35 nM; MAP4K4: 49 nM; MINK1: 41 nM; PDGFRα: 35 nM; RET: 8 nM; SIK3: 23 nM; VEGFR1: 26 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 90 mg/mL (178.02 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

ODM-203 serves as a research tool to investigate FGFR inhibition, advancing the understanding of its therapeutic potential in FGFR-driven malignancies.