FGFR inhibitor PD173074, Purity ≥98%

Synonym: 219580-11-7; FGFR inhibitor; PD-173074

MDL: MFCD08705327
CAS Number: 219580-11-7
Compound CID: 1401

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PD173074, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets c-Src, VEGFR2, EGFR, FGFR1, Insulin receptor, MEK, and PKC.

Molecular Weight

523.7

Molecular Formula

C₂₈H₄₁N₇O₃

Targets

c-Src: 19.8 μM; VEGFR2: 100-200 nM; EGFR: >50 μM; FGFR1: 25 nM; Insulin receptor: >50 μM; MEK: >50 μM; PKC: >50 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 86 mg/mL (164.22 mM); Water: Insoluble; Ethanol: 86 mg/mL (164.22 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PD173074 aids in the study of FGFR inhibition in cancer research, targeting FGFR’s role in tumor progression.