FGFR inhibitor Roblitinib, Purity ≥98%

Synonym: 1708971-55-4; FGFR inhibitor; FGF-401; FGF401; FGF 401

CAS Number: 1708971-55-4
Compound CID: 118036971

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Roblitinib, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, FGFR3, FGFR4, and rat FGFR4.

Molecular Weight

506.56

Molecular Formula

C₂₅H₃₀N₈O₄

Targets

FGFR1: >10 μM; FGFR2: >10 μM; FGFR3: >10 μM; FGFR4: 1.9 nM; rat FGFR4: >10 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 5 mg/mL (9.87 mM); Water: Insoluble; Ethanol: 2 mg/mL (3.94 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Roblitinib is used in exploring FGFR as an inhibitor, providing insights into FGFR-driven cancer mechanisms and therapeutic potential.