FGFR inhibitor S49076, Purity ≥98%

Synonym: 1265965-22-7; FGFR inhibitor; S 49076; S-49076

CAS Number: 1265965-22-7
Compound CID: 49870909

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

S49076, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets Axl, FGFR1, FGFR1V561M, FGFR2, FGFR2N549H, FGFR3, and MER.

Molecular Weight

438.5

Molecular Formula

C₂₂H₂₂N₄O₄S

Targets

Axl: 7 nM; FGFR1: 18 nM; FGFR1V561M: 23 nM; FGFR2: 17 nM; FGFR2 N549H: 19 nM; FGFR3: 15 nM; MER: 2 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 79 mg/mL (180.16 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

S49076 targets FGFRs to investigate its role in cancer cell growth and potential therapeutic interventions.