Properties
Description
TSU-68, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, Flk1, and PDGFRβ.
Molecular Formula
C18H18N2O3
Targets
FGFR1: 1.2 μM (Ki); Flk1: 2.1 μM (Ki); PDGFRβ: 8 μM (Ki)
Solubility
DMSO: 55 mg/mL (177.22 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
TSU-68 is used as an FGFR inhibitor in investigations concerning angiogenesis and cancer cell growth.
