Properties
Description
FITC-dextran, a water-soluble yellow powder, consists of a fluorescein moiety anchored stably by a thiocarbamoyl linkage without causing any depolymerization of the dextran. This compound exhibits its highest intensity at a pH greater than 8, reaching excitation and emission maximums of 490-495 nm and 520 ± 13 nm, respectively. FITC-dextran is a high-quality product with a molecular weight of approx. 2,000,000 and a degree of substitution of 0.001-0.020.
Molecular Weight
Approx. 2,000,000
Degree of Substitution
0.1-2%
Solubility
FITC-dextran dissolves readily in water.
Identity
Confirmed by NMR/HPLC/MS.
Applications
FITC-dextran with a molecular weight of approx. 2,000,000 and DS of 0.001-0.020 can be used for the study of permeability, microcirculation, as well as the delivery of drugs while serving as a significant marker for molecular size and a sensitive pH indicator in various biological and chemical settings.
