Properties
Description
Pimecrolimus, soluble in DMSO and ethanol and insoluble in water, is primarily used to suppress the immune response in conditions such as eczema by inhibiting calcineurin, an enzyme critical for T-cell activation.
Molecular Formula
C43H68ClNO11
Solubility
DMSO: 94 mg/mL (115.98 mM); Water: Insoluble; Ethanol: 94 mg/mL (115.98 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Pimecrolimus is used in research to inhibit FKBP, a protein involved in immune regulation, making it a potential target for treating inflammatory skin conditions.
