Properties
Description
Flibanserin, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1A receptor, 5-HT2A receptor, and dopamine D4 receptors.
Molecular Formula
C20H21F3N4O
Targets
5-HT1A receptor: 1 nM; 5-HT2A receptor: 49 nM; dopamine D4 receptors: 4-24 nM
Solubility
DMSO: 70 mg/mL (179.3 mM); Water: insoluble; Ethanol: 21 mg/mL (53.79 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Flibanserin can be used for its ability to increase sexual desire and improve sexual satisfaction.
Storage
Store at -20°C, and keep desiccated.