FLT3 inhibitor TG101209, Purity ≥98%

Synonym: 936091-14-4; TG101209; TG-101209; TG 101209; N-tert-Butyl-3-(5-methyl-2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide; N-tert-Butyl-3-[[5-methyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide; FLT3 inhibitor

MDL: MFCD15528085
CAS Number: 936091-14-4
Compound CID: 16722832

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TG101209, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FLT3. It targets JAK2, RET, FLT3, and JAK3.

Molecular Weight

509.67

Molecular Formula

C₂₆H₃₅N₇O₂S

Targets

JAK2: 6 nM; RET: 17 nM; FLT3: 25 nM; JAK3: 169 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 94 mg/mL (184.42 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

TG101209 can be used to explore the inhibition of JAK2 and its potential therapeutic applications in myeloproliferative disorders.