FLT3 inhibitor TG101209, Purity ≥98%

Synonym: 936091-14-4; TG101209; TG-101209; TG 101209; N-tert-Butyl-3-(5-methyl-2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide; N-tert-Butyl-3-[[5-methyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide; FLT3 inhibitor

MDL: MFCD15528085
CAS Number: 936091-14-4
Compound CID: 16722832

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TG101209, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FLT3. It targets JAK2, RET, FLT3, and JAK3.

Molecular Weight

509.67

Molecular Formula

C₂₆H₃₅N₇O₂S

Targets

JAK2: 6 nM; RET: 17 nM; FLT3: 25 nM; JAK3: 169 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 94 mg/mL (184.42 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

TG101209 can be used to explore the inhibition of JAK2 and its potential therapeutic applications in myeloproliferative disorders.

Storage

Store at -20ºC.