Fosaprepitant dimeglumine, soluble in DMSO and water, and insoluble in ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets NK-1 receptor.
Fosaprepitant dimeglumine can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.
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