Properties
Description
Fraxetin alleviates lipid peroxidation, enhances hepatic antioxidant capabilities, inhibits CYP2E1 activity, and reduced the inflammatory mediators, including TNF-α and IL-1β via up-regulation of heme oxygenase-1 (HO-1) protein.
Molecular Formula
C10H8O5
Source
The bark of Fraxinus brngeana DC.
Form
Light yellow flaky crystal
Purity
>98%, determined by HPLC.
Solubility
It is soluble in ethanol and hydrochloric acid aqueous solution, slightly soluble in boiling water, hardly soluble in ether.
Identity
Confirmed by NMR and MS.
Applications
Fraxetin can be used for antioxidant activity experiments, etc.