FXR inhibitor, AMG-333, Purity ≥98%

Synonym: 1416799-28-4; AMG333; AMG 333; 6-[[(S)-(3-Fluoropyridin-2-yl)-[3-fluoro-4-(trifluoromethoxy)phenyl]methyl]carbamoyl]pyridine-3-carboxylic acid; FXR inhibitor

CAS Number: 1416799-28-4
Compound CID: 71144018

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AMG-333, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting FXR. The molecular weight of the compound is 453.32, and its molecular formula is C₂₀H₁₂F₅N₃O₄.

Molecular Weight

453.32

Molecular Formula

C₂₀H₁₂F₅N₃O₄

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 81 mg/mL (178.68 mM); Water: insoluble; Ethanol: 81 mg/mL (178.68 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

AMG-333 plays a key role in modulating bile acid metabolism and improving liver health.