FXR inhibitor, Tropifexor, Purity ≥98%

Synonym: 1383816-29-2; LJN452; LJN-452; LJN 452; 2-[(1R,5S)-3-[[5-Cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxy]-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid; FXR inhibitor

MDL: MFCD31619256
CAS Number: 1383816-29-2
Compound CID: 121418176

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Tropifexor, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting FXR. The molecular weight of the compound is 603.58, and its molecular formula is C₂₉H₂₅F₄N₃O₅S.

Molecular Weight

603.58

Molecular Formula

C₂₉H₂₅F₄N₃O₅S

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 99 mg/mL (164.01 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Tropifexor plays a key role in regulating bile acid and lipid metabolism.