Glycan Arrays

CD BioGlyco is a world-leading company that can provide the best solutions for global customers in the field of microarrays. We have successfully developed many Glycobiology Arrays and corresponding testing services to accelerate the high-throughput detection of glycosylated proteins in biological samples. Glycan array is one kind of them. We guarantee to provide first-class array screening service to customers all over the world.

Importance of Glycans

Glycans or carbohydrates attached to cell membranes and other types of proteins are the main determinants of binding activity and related cell functions. There are many types of research on glycocalyx in the field of glycobiology. The components of glycocalyx play an important role in protein folding and transportation, cell signal transduction, virus infection and immune process. The glycocalyx is an extracellular polymer coating surrounding many prokaryotic and eukaryotic cells composed of glycoproteins, glycolipids, proteoglycans, and glycosaminoglycans. The study of the functions and properties of these glycans is the basis of immunological research and can be used to understand the interactions between various cells. New technologies such as microarrays for glycan-binding applications enable researchers to study and reveal new information about the vast and evolving field of glycan science. However, the detection tools used in glycobiology research are still being updated. The Glycan-100 and Glycan-300 arrays we supply will help researchers to carry out corresponding research.

The Glycan-100 array contains 100 glycan targets that have been widely studied. The Glycan-300 array is based on the Glycan-100 array with additional targets for N-glycans, glycolipoglycans and human milk oligosaccharides. These glycan targets are often identified in the literature as structures showing important binding functions. For example, it has been shown that a variety of sialic acid glycosides bind to viruses in a specific manner and are involved in inflammation and infectious diseases. Some galectins participate in apoptosis, cell adhesion and T cell activation inhibition by binding β-galactoside. The oligosaccharides of human milk combine with microorganisms to promote the growth of normal flora and inhibit pathogens in the gastrointestinal tract. This set of arrays provides powerful tools for researchers in glycobiology and interdisciplinary fields.

Applications

  • Identify glycan-binding partners in biological samples
  • Identify whether the target protein is a glycan-binding protein
  • The probe binds pathogens including bacteria, viruses, and whole cells to glycans;
  • Analyze the substrate specificity of glycan metabolism-related enzymes (glycosyltransferase, glycosidase);
  • Analyze signal transduction in inflammation and/or immune response.

CD BioGlyco provides high-quality array screening services for the detection of glycans in liquid samples. We provide customized array services according to your research goals for glycomic analysis. With a large team of scientists and a well-equipped array production platform and testing experiment platform, we provide a comprehensive combination of laboratories and manufacturing services. We have comprehensive capabilities and are committed to working with customers all over the world to meet your specific requirements. Please contact us for more details.

Cat. No. Product Name Inquiry
CMA-GA-100 Glycan Array 100
CMA-GA-300 Glycan Array 300

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