Sphingolipids are a class of amphiphilic lipids containing a sphingosine skeleton, a long chain of fatty acids and a polar alcohol are connected at each end. They are widely distributed, especially in the tissues of the central nervous system. Studies have found that sphingolipids and their metabolites are an important class of active molecules, which are involved in the regulation of cell growth, differentiation, senescence, apoptosis and many other signal transduction processes.