Properties
Description
Granisetron hydrochloride, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT3.
Molecular Formula
C18H24N4O·HCl
Solubility
DMSO: 1 mg/mL (2.86 mM); Water: 67 mg/mL (192.05 mM); Ethanol: 1 mg/mL (2.86 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Granisetron hydrochloride can be used for its effect on blocking serotonin receptors in the chemoreceptor trigger zone (CTZ) and gastrointestinal tract, thereby reducing the nausea and vomiting commonly associated with chemotherapy.
Storage
Store at -20℃, and keep desiccated.
