Granisetron, soluble in DMSO and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT3 receptor.
Molecular Weight
312.41
Molecular Formula
C18H24N4O
Targets
5-HT3 receptor: 17 μM
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 9 mg/mL (28.81 mM); Water: <1 mg/mL
Applications
Granisetron can be studied for its effect on preventing nausea and vomiting following surgical procedures.
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