GSK-3 inhibitor 1-Azakenpaullone, Purity ≥98%

Synonym: 676596-65-9; 1-Azakenpaullone; Azakenpaullone; 1-AKP; 9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one; GSK-3 inhibitor

CAS Number: 676596-65-9
Compound CID: 6538897

Product Size

2 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

1-Azakenpaullone, soluble in DMSO and insoluble in ethanol and water, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets GSK-3α and GSK-3β.

Molecular Weight

328.16

Molecular Formula

C₁₅H₁₀BrN₃O

Targets

GSK-3α; GSK-3β

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 38 nM (Ki); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

1-Azakenpaullone can be used to investigate its role as a GSK-3β inhibitor in cancer and neurobiology research.

Storage

Store at -20ºC.