Properties
Description
AZD1080, soluble in DMSO and insoluble in ethanol and water, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets GSK-3α and GSK-3β.
Molecular Formula
C19H18N4O2
Targets
GSK-3α: 6.9 nM; GSK-3β: 31 nM
Solubility
DMSO: 49 mg/mL (146.54 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AZD1080 is used to investigate its effects on GSK-3 inhibition in Alzheimer's disease.
