GSK-3 inhibitor AZD1080, Purity ≥98%

Synonym: 612487-72-6; AZD 1080; AZD-1080; GSK-3 inhibitor

CAS Number: 612487-72-6
Compound CID: 135564570

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD1080, soluble in DMSO and insoluble in ethanol and water, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets GSK-3α and GSK-3β.

Molecular Weight

334.4

Molecular Formula

C₁₉H₁₈N₄O₂

Targets

GSK-3α: 6.9 nM; GSK-3β: 31 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 49 mg/mL (146.54 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

AZD1080 is used to investigate its effects on GSK-3 inhibition in Alzheimer's disease.