Properties
Description
BIO-acetoxime, soluble in warmed DMSO and insoluble in water and ethanol, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets GSK-3α and GSK-3β.
Molecular Formula
C18H12BrN3O3
Targets
GSK-3α: 10 nM; GSK-3β: 10 nM
Solubility
Warmed DMSO: 18 mg/mL (45.2 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BIO-acetoxime is used to explore its role as a GSK-3 inhibitor in biological studies.