GSK-3 inhibitor CHIR-99021 trihydrochloride, Purity ≥98%

Synonym: 1782235-14-6; CT99021 trihydrochloride; CT 99021; CT 99021; CHIR99021; CHIR 99021; GSK-3 inhibitor

CAS Number: 1782235-14-6
Compound CID: 78243722

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CHIR-99021 trihydrochloride modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets cdc2, GSK-3α, and GSK-3β.

Molecular Weight

574.72

Molecular Formula

C₂₂H₂₁Cl₅N₈

Targets

cdc2: 8800 nM; GSK-3α: 10 nM; GSK-3β: 6.7 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

CHIR-99021 trihydrochloride is employed in research on GSK-3 inhibition and cell fate decisions.

Storage

Store at -20ºC.