Properties
Description
LY2090314, soluble in DMSO and warmed ethanol and insoluble in water, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets GSK-3α and GSK-3β.
Molecular Formula
C28H25FN6O3
Targets
GSK-3α: 1.5 nM; GSK-3β: 0.9 nM
Solubility
DMSO: 93 mg/mL (181.45 mM); Water: Insoluble; Warmed ethanol: 2 mg/mL (3.9 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
LY2090314 can be used to inhibit GSK-3 in studies focusing on oncology and regenerative medicine.
