GSK-3 inhibitor SB 216763, Purity ≥98%

Synonym: 280744-09-4; SB-216763; SB216763; GSK-3 inhibitor

CAS Number: 280744-09-4
Compound CID: 176158

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SB 216763, soluble in DMSO and insoluble in ethanol and water, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets GSK-3α and GSK-3β.

Molecular Weight

371.2

Molecular Formula

C₁₉H₁₂Cl₂N₂O₂

Targets

GSK-3α: 34.3 nM; GSK-3β: 34.3 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 21 mg/mL (56.56 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

SB 216763 is employed to inhibit GSK-3 and study its role in neurodevelopment and cancer.