Properties
Description
SB 415286, soluble in DMSO and ethanol and insoluble in water, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets GSK-3α and GSK-3β.
Molecular Formula
C16H10ClN3O5
Targets
GSK-3α: 78 nM; GSK-3β: 78 nM
Solubility
DMSO: 63 mg/mL (175.13 mM); Water: Insoluble; Ethanol: 63 mg/mL (175.13 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
SB 415286 is used to investigate GSK-3 inhibition and its therapeutic potential in various diseases.
