GSK-3 inhibitor SB 415286, Purity ≥98%

Synonym: 264218-23-7; SB-415286; SB415286; GSK-3 inhibitor

CAS Number: 264218-23-7
Compound CID: 4210951

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SB 415286, soluble in DMSO and ethanol and insoluble in water, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets GSK-3α and GSK-3β.

Molecular Weight

359.7

Molecular Formula

C₁₆H₁₀ClN₃O₅

Targets

GSK-3α: 78 nM; GSK-3β: 78 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 63 mg/mL (175.13 mM); Water: Insoluble; Ethanol: 63 mg/mL (175.13 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

SB 415286 is used to investigate GSK-3 inhibition and its therapeutic potential in various diseases.