GSK-3 inhibitor Tideglusib, Purity ≥98%

Synonym: 865854-05-3; Tideglusib; NP-12; NP031112; 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione; GSK-3 inhibitor

CAS Number: 865854-05-3
Compound CID: 11313622

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Tideglusib, soluble in warmed DMSO and insoluble in water and ethanol, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets GSK-3β (C199A) and GSK-3β(WT).

Molecular Weight

334.39

Molecular Formula

C₁₉H₁₄N₂O₂S

Targets

GSK-3β (C199A): 60 nM; GSK-3β(WT): 5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 7 mg/mL (20.93 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Tideglusib is used to study its effects on GSK-3 inhibition in Alzheimer's and other neurological disorders.