Glycosphingolipids (GSLs) are an important class of biomolecules with various physiological functions in living organisms, such as regulation of cell growth, differentiation, apoptosis, maintenance of cell morphology, and other important functions. CD BioGlyco provides customers with microarray chip-based analysis of GSL components.
Microarray chips are a high-throughput analytical technique that works by targeting and immobilizing target molecules on the wafer surface, then using labeled probes to bind to the target molecules, and finally using bioimaging to detect and identify the biomolecules to determine the hybridization of the probes to each immobilized molecule on the chip. GSL is a complex class of glycolipids that are commonly analyzed for their components using glycosyl microarray chips. Glycosyl microarray use molecules with specific glycosyl structures as probes that allow the analysis of the type and relative amount of glycosyl molecules present in a sample. These probes are usually made by combining mannose, galactose, and N-acetylcysteine, which have a high glycan structural diversity. Glycosyl microarray chips typically use probes with different glycosyl structures for the identification and analysis of GSLs. These probes include various glycans, proteins, and antibodies to determine the different structures and characteristics of GSLs.
Fig.1 The flow of GSL components analysis by microarray chips. (CD BioGlyco)
When analyzing the component of GSL by microarray chip, more specific probes are usually selected, such as small molecule metabolite microarrays, glycolipid microarrays, etc. CD BioGlyco offers microarray chips services including:
In this service, we identify and analyze GSL using probes with different glycosyl structures that include a variety of glycans, proteins, and antibodies to determine the different structures and characteristics of GSL. This service is characterized by high throughput, high sensitivity, and rapid analysis.
This service can be used to detect the ability of GSL to bind to specific proteins, which in turn helps researchers understand the mechanism of GSL action in cells and its interactions with other proteins with high reproducibility and accuracy.
CD BioGlyco has extensive experience in the component analysis of GSLs by advanced microarray chips and has powerful data processing tools to analyze experimental results. Our professional services bring great convenience to our clients in the research of GSLs. If you are interested in our services, please contact us to obtain more information.
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