Properties
Description
Guanfacine hydrochloride, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets α2A-adrenoceptor.
Molecular Formula
C9H10Cl3N3O
Solubility
DMSO: 48 mg/mL (169.88 mM); Water: 26 mg/mL (92.01 mM); Ethanol: 48 mg/mL
Applications
Guanfacine hydrochloride can be studied for its effect on stimulating alpha-2 adrenergic receptors in the prefrontal cortex, which helps improve attention, impulse control, and working memory in individuals with ADHD.
