Features of Guluronic Acid

Guluronic acid is derived from gulose, where the aldehyde group on C1 is replaced by a carboxylic group. In most animals and plants, guluronic acid exists in the form of γ-lactone. L-guluronic acid can be converted to L-ascorbic acid by oxidative dehydrogenation in some animals, but the enzyme that catalyzes this conversion is not available in humans. There is also a metabolic pathway that L-guluronic acid converts to D-xylulose, and the intermediate metabolite L-xylulose can be detected in the urine of patients with pentosuria.

Fig.1 Chemical structure of L-guluronic acid. (Wikipedia)

Guluronic Acid Analysis Service at CD BioGlyco

CD BioGlyco masters the efficient process of guluronic acid metabolism analysis. We provide you with professional sample processing and detection as well as data analysis services.

• About the sample
  
  • Solid: Animal or plant tissues, cells, microorganisms, feces, etc.
  • Liquid: Blood, urine, bile, cholic acid, etc.
  • Quantity: Solid ≥10 mg; Liquid ≥10 μL.
  • For other types of samples and the quantity, please contact CD BioGlyco for information.
  • Please prepare dry ice during the mailing process. If the solid sample is too large, please cut it into 1 cm chunks.
• About the standard solution: CD BioGlyco provides standard solutions free of charge. The process is followed by weighing a certain amount of guluronic acid powder and fully dissolving it in deionized water (ultrasonic assisted dissolution if necessary) to make guluronic acid aqueous solution with known concentration.
• About the detection
  
  • Sample separation: CD BioGlyco has many approaches for separation such as high-performance liquid chromatography (HPLC), capillary electrophoresis (CE), gas chromatography (GC), high-performance anion exchange chromatography (HPAEC), and others.
  • Detectors: According to your requirements for sensitivity, accuracy, and economy, we offer various detectors, including ultraviolet detector (UVD), fluorescence detector (FLD), refractive index detector (RID), evaporative light-scattering detector (ELSD), mass spectrometric (MS) detector, electrochemical detector (ECD), etc.
• About the technical report: CD BioGlyco provides a detailed technical report consisting of experimental procedures and parameters, spectrograms, qualitative or quantitative information on guluronic acid, raw data, and the final summary. If you need other relevant content attached, please contact us.

Fig.2 Different choices for guluronic acid metabolism analysis. (CD BioGlyco)

Applications

• Qualitative and quantitative analysis of guluronic acid
• Detection of guluronic acid in complex samples
• Study on the guluronic acid metabolic pathway
• Study on bioactivity of guluronic acid

Highlights

• What do you need to do: Order and send your samples
• One-stop service at CD BioGlyco: Sample processing → detection → data analysis → project report
• Professional experimenters
• End-to-end analysis services

With extensive experience in the scientific community, CD BioGlyco enjoys a global reputation. We offer professional Monosaccharide, Disaccharide, Oligosaccharide, and Polysaccharide Metabolism Analysis services. If you are looking for a Solution, please do not hesitate to contact us immediately.