HDAC inhibitor ACY-775, Purity ≥98%

Synonym: 1375466-18-4; ACY-775; 2-((1-(3-Fluorophenyl)cyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide; 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide; 2-[[1-(3-Fluorophenyl)cyclohexyl]amino]-N-hydroxypyrimidine-5-carboxamide; HDAC inhibitor

MDL: MFCD30533691
CAS Number: 1375466-18-4
Compound CID: 57382288

Product Size

2 mg; 5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ACY-775, soluble in DMSO and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC2, HDAC3, and HDAC6.

Molecular Weight

330.36

Molecular Formula

C₁₇H₁₉FN₄O₂

Targets

HDAC1: 2123 nM; HDAC2: 2570 nM; HDAC3: 11223 nM; HDAC6: 7.5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 63 mg/mL (190.7 mM); Water: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

ACY-775 can be used to study its effects as a selective HDAC6 inhibitor.

Storage

Store at -20ºC.