HDAC inhibitor AES-135, Purity ≥98%

Synonym: 2361659-61-0; AES-135; EX-A5097; BDBM50519452; MS-31144; 4-[(4-tert-Butylphenyl)methyl-[2-[(4-fluorophenyl)sulfonyl-[(2,3,4,5,6-pentafluorophenyl)methyl]amino]acetyl]amino]-N-hydroxybenzamide; HDAC inhibitor

CAS Number: 2361659-61-0
Compound CID: 137628685

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AES-135 induces DNA damage and the inhibition of DNA repair processes. It targets HDAC11, HDAC3, HDAC6, and HDAC8.

Molecular Weight

693.66

Molecular Formula

C₃₃H₂₉F₆N₃O₅S

Targets

HDAC11: 636 nM; HDAC3: 654 nM; HDAC6: 190 nM; HDAC8: 1100 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AES-135 can be used to investigate its inhibitory effects on HDAC1.

Storage

Store at -20ºC.