HDAC inhibitor CAY10603, Purity ≥98%

Synonym: 1045792-66-2; CAY10603; BML-281; tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate; HDAC6 Inhibitor; tert-Butyl N-[4-[3-[[7-(hydroxyamino)-7-oxoheptyl]carbamoyl]-1,2-oxazol-5-yl]phenyl]carbamate; HDAC inhibitor

MDL: MFCD17010286
CAS Number: 1045792-66-2
Compound CID: 24951314

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CAY10603, soluble in DMSO and warmed ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC10, HDAC2, HDAC3, HDAC6, and HDAC8.

Molecular Weight

446.5

Molecular Formula

C₂₂H₃₀N₄O₆

Targets

HDAC1: 271 nM; HDAC10: 90.7 nM; HDAC2: 252 nM; HDAC3: 0.42 nM; HDAC6: 0.002 nM; HDAC8: 6851 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 88 mg/mL (197.08 mM); Water: Insoluble; Warmed ethanol: 5 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

CAY10603 is used in scientific research for its potent inhibitory effects on histone deacetylases (HDACs), which can elucidate the role of HDAC inhibition in cancer and neurological disorders.