Properties
Description
CRA-026440 induces DNA damage and the inhibition of DNA repair processes. It targets HDAC3, HDAC1, HDAC2, and HDAC6.
Molecular Formula
C23H24N4O4
Targets
HDAC3: 289 nM; HDAC1: 2 nM; HDAC2: 2.2 nM; HDAC6: >20 μM
Identity
Confirmed by NMR/HPLC/MS.
Applications
CRA-026440 is employed in research to examine its capability to inhibit HDACs and its potential impact on cancer cell growth and survival.