HDAC inhibitor Entinostat, Purity ≥98%

Synonym: 209783-80-2; Entinostat; ms-275; SNDX-275; Entinostat (MS-275); MS 275; HDAC inhibitor

MDL: MFCD08272435
CAS Number: 209783-80-2
Compound CID: 4261

Product Size

10 mg; 25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Entinostat, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1 and HDAC3.

Molecular Weight

376.4

Molecular Formula

C₂₁H₂₀N₄O₃

Targets

HDAC1: 0.51 μM; HDAC3: 1.7 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 71 mg/mL (188.62 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Entinostat is investigated for its role in inhibiting HDACs, particularly in enhancing anticancer immune responses and sensitivity to other treatments.

Storage

Store at -20ºC.