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Cat. No.: X23-10-ZQ275

HDAC inhibitor Fimepinostat, Purity ≥98%

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Synonym: 1339928-25-4; CUDC-907; Fimepinostat; CUDC 907; CUDC907; PI3K/HDAC Inhibitor; Fimepinostat [USAN]; HDAC inhibitor

  • MDL: MFCD22420823
  • CAS Number: 1339928-25-4
  • Compound CID: 54575456
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Fimepinostat, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9.
Molecular Weight
508.6
Molecular Formula
C23H24N8O4S
Targets
HDAC1: 1.7 nM; HDAC10: 2.8 nM; HDAC11: 5.4 nM; HDAC2: 5.0 nM; HDAC3: 1.8 nM; HDAC4: 409 nM; HDAC5: 674 nM; HDAC6: 27 nM; HDAC7: 426 nM; HDAC8: 191 nM; HDAC9: 554 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 87 mg/mL (171.07 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Fimepinostat is applied in studies to assess its dual inhibition of HDACs and phosphoinositide 3-kinase (PI3K) as a strategy for treating various cancers.
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