Properties
Description
LMK-235, soluble in DMSO and ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC4 and HDAC5.
Molecular Formula
C15H22N2O4
Targets
HDAC4: 11.9 nM; HDAC5: 4.2 nM
Solubility
DMSO: 50 mg/mL (169.86 mM); Water: Insoluble; Ethanol: 50 mg/mL (169.86 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
LMK-235 is investigated for its selective inhibition of HDAC4 and HDAC5, aiding research into its applications in cancer and neurodegenerative diseases.