HDAC inhibitor Mocetinostat, Purity ≥98%

Synonym: 726169-73-9; Mocetinostat; MGCD0103; MGCD-0103; MGCD 0103; N-(2-AMINOPHENYL)-4-([[4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL]AMINO]METHYL)BENZAMIDE; HDAC inhibitor

MDL: MFCD10565970
CAS Number: 726169-73-9
Compound CID: 9865515

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

Mocetinostat, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, and HDAC8.

Molecular Weight

396.4

Molecular Formula

C₂₃H₂₀N₆O

Targets

HDAC1: 0.15 μM; HDAC11: 0.59 μM; HDAC2: 0.29 μM; HDAC3: 0.15 μM; HDAC4: >10 μM; HDAC5: >10 μM; HDAC6: >10 μM; HDAC7: >10 μM; HDAC8: >10 μM

Form

Lyophilized powder

Purity

Solubility

DMSO: 12 mg/mL (30.27 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Mocetinostat can be used to inhibit HDACs, contributing to research on epigenetic modulation in cancer therapies.