HDAC inhibitor MPT0E028, Purity ≥98%

Synonym: 1338320-94-7; MPT0E028; 3-(1-(Benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide; T65L58FI65; 3-(2,3-Dihydro-1-(phenylsulfonyl)-1H-indol-5-yl)-N-hydroxy-2-propenamide; (E)-3-[1-(Benzenesulfonyl)-2,3-dihydroindol-5-yl]-N-hydroxyprop-2-enamide; HDAC inhibitor

CAS Number: 1338320-94-7
Compound CID: 53464642

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MPT0E028 induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC2, HDAC6, and HDAC8.

Molecular Weight

344.38

Molecular Formula

C₁₇H₁₆N₂O₄S

Targets

HDAC1: 53.0 nM; HDAC2: 106.2 nM; HDAC6: 29.5 nM; HDAC8: 2532.6 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

MPT0E028 is used to study its dual inhibition on HDACs and PI3K/AKT/mTOR pathway, providing insights into cancer cell growth and survival.

Storage

Store at -20ºC.