HDAC inhibitor Panobinostat, Purity ≥98%

Synonym: 404950-80-7; Panobinostat; LBH589; LBH-589; Farydak; Faridak; Panobinostat (LBH589); HDAC inhibitor

MDL: MFCD09833242
CAS Number: 404950-80-7
Compound CID: 6918837

Product Size

10 mg; 25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Panobinostat, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC (MOLT-4 cells) and HDAC (Reh cells).

Molecular Weight

349.4

Molecular Formula

C₂₁H₂₃N₃O₂

Targets

HDAC (MOLT-4 cells): 5 nM; HDAC (Reh cells): 20 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 60 mg/mL (171.7 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Panobinostat is used in scientific studies to understand its potent inhibitory effects on HDACs and its potential as a therapeutic agent in cancer.

Storage

Store at -20ºC.