Properties
Description
Panobinostat, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC (MOLT-4 cells) and HDAC (Reh cells).
Molecular Formula
C21H23N3O2
Targets
HDAC (MOLT-4 cells): 5 nM; HDAC (Reh cells): 20 nM
Solubility
DMSO: 60 mg/mL (171.7 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Panobinostat is used in scientific studies to understand its potent inhibitory effects on HDACs and its potential as a therapeutic agent in cancer.