HDAC inhibitor PCI-34051, Purity ≥98%

Synonym: 950762-95-5; PCI-34051; N-Hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide; PCI 34051; N-Hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide; PCI34051; HDAC inhibitor

MDL: MFCD11114393
CAS Number: 950762-95-5
Compound CID: 24753719

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PCI-34051, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC6, HDAC10, HDAC2, HDAC3, and HDAC8.

Molecular Weight

296.3

Molecular Formula

C₁₇H₁₆N₂O₃

Targets

HDAC1: 4 μM; HDAC6: 2.9 μM; HDAC10: 13 μM; HDAC2: >50 μM; HDAC3: >50 μM; HDAC8: 10 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 58 mg/mL (195.73 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PCI-34051 is utilized in studies for its selective inhibition of HDAC8, thus aiding in cancer research and epigenetic studies.

Storage

Store at -20ºC.