HDAC inhibitor Pracinostat, Purity ≥98%

Synonym: 929016-96-6; Pracinostat; SB939; SB 939; Pracinostat (SB939); SB-939; Pracinostat [INN]; HDAC inhibitor

MDL: MFCD17215206
CAS Number: 929016-96-6
Compound CID: 49855250

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Pracinostat, soluble in DMSO and ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9.

Molecular Weight

358.5

Molecular Formula

C₂₀H₃₀N₄O₂

Targets

HDAC1: 49 nM; HDAC10: 40 nM; HDAC11: 93 nM; HDAC2: 96 nM; HDAC3: 43 nM; HDAC4: 56 nM; HDAC5: 47 nM; HDAC6: 1.008 μM; HDAC7: 137 nM; HDAC8: 137 nM; HDAC9: 70 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 68 mg/mL (189.68 mM); Water: Insoluble; Ethanol: 26 mg/mL (72.52 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Pracinostat is used in research for its role in inhibiting HDACs, particularly in chronic myelomonocytic leukemia (CMML).

Storage

Store at -20ºC.