HDAC inhibitor Romidepsin, Purity ≥98%

Synonym: 128517-07-7; Romidepsin; Istodax; Depsipeptide; Chromadax; FK228; Antibiotic FR 901228; HDAC inhibitor

MDL: MFCD18433404
CAS Number: 128517-07-7
Compound CID: 5352062

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Romidepsin, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1 and HDAC2.

Molecular Weight

540.7

Molecular Formula

C₂₄H₃₆N₄O₆S₂

Targets

HDAC1: 36 nM; HDAC2: 47 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 9 mg/mL (16.64 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Romidepsin is used to inhibit HDACs, particularly in the treatment and research of T-cell lymphoma.

Storage

Store at -20ºC.