HDAC inhibitor SR-4370, Purity ≥98%

Synonym: 1816294-67-3; SR-4370; SR4370; N'-Butyl-2',3'-difluoro-[1,1'-biphenyl]-4-carbohydrazide; SR 4370; HDAC inhibitor

CAS Number: 1816294-67-3
Compound CID: 118418385

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SR-4370, soluble in DMSO and ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8.

Molecular Weight

304.34

Molecular Formula

C₁₇H₁₈F₂N₂O

Targets

HDAC1: 130 nM; HDAC2: 580 nM; HDAC3: 6 nM; HDAC6: 3400 nM; HDAC8: 2300 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 56 mg/mL (184.01 mM); Water: Insoluble; Ethanol: 56 mg/mL (184.01 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SR-4370 is utilized to investigate its effects on HDAC inhibition, particularly in cancer cell studies.

Storage

Store at -20ºC.